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Dermatology ยป Impetigo vs. cellulitis: what are the key differences?

Impetigo vs. cellulitis: what are the key differences?

Practical differences between impetigo vs cellulitis, what each usually looks like, what signs suggest urgency and what to expect from medical management without going into dosage.

by Wendy Lazcano
February 10, 2026
Reading Time: 4 mins read
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Wendy Lazcano
Editor at Vitals Today
Wendy is an experienced journalist with a background in print (Diario de Cuba, Review Energy), radio (W Radio / PRISA Group) and television (Canal 33). She specialises in politics and regulation and is known for making complex issues easy to understand.
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Impetigo and cellulitis are bacterial skin infections, but they usually affect different layers and are managed differently. If there is fever, severe pain, or the area is spreading quickly, it is sensible to seek same day medical advice.

Although both may initially appear as a red, irritated area, impetigo is usually more superficial, while cellulite tends to affect deeper tissues. Distinguishing between them is important because the risks and the type of professional treatment are not typically the same.

Impetigo vs. Cellulite

Impetigo and cellulitis are generally distinguished by the depth of the infection and how the affected area progresses over hours or a few days. This table summarizes typical signs that can help guide diagnosis but does not replace a clinical evaluation.

ImpetigoCellulitis
SuperficialDeeper
Honey-colored scabsโ€œRed and hot skin
Frequent itchingMore pronounced pain
Highly contagiousIt usually isn't.
More common in childrenMore common in adults

What does impetigo usually look like?

Impetigo typically presents as blisters or lesions that break and leave a yellowish or "honey-colored" crust, often in exposed areas such as around the nose or mouth. It can spread through contact, which is why hygiene and not sharing towels are so important.

Which signs are most consistent with cellulite?

Cellulitis typically presents as a red, swollen, warm, and painful area that can grow rapidly, especially on the legs, and is sometimes accompanied by fever or malaise. Because of its potential to worsen and spread, many guidelines recommend same-day evaluation if symptoms progress.

When to consult a doctor if you're unsure between impetigo and cellulite

If the rash is spreading, pain is getting worse, fever appears, the skin becomes very tender, or the person feels unwell, it is safer to seek urgent medical care. A clinician may prescribe antibiotics and, in some cases, topical options such as mupirocin, depending on the type and extent of the infection.

This text is for informational purposes only and does not replace medical advice. For a proper diagnosis and treatment plan, consult official health sources and follow the instructions of your doctor or pharmacist, who are the ones who can assess the severity of your condition, determine the necessary tests, and recommend the safest treatment.

Tags: Infection
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