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Health » Postpartum Mastitis: What is it and what to do?

Postpartum Mastitis: What is it and what to do?

Dr. Marisol Expósito talks about puerperal mastitis, which affects breastfeeding mothers between weeks 31 and 33, explaining its causes, symptoms, and treatments.

by Dr. Marisol Exposito
April 28, 2025
Reading Time: 3 mins read
A mother breastfeeding her baby, with natural light coming in through the window, capturing an intimate moment between them.
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Dr. Marisol Exposito
Dr. Marisol Exposito
Medical Expert at Vitals Today
Dr Marisol Expósito is a specialist in internal medicine with clinical experience in Cuba and Spain and a strong teaching background. Her focus on the care of older adults enriches her regular column at Vitals Today and her role on our Medical Advisory Board.
Dr. Marisol Exposito
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Mastitis is one of the leading causes of breastfeeding cessation. It is characterized by inflammation of one or more mammary lobules, according to the WHO , its incidence varies from 3% to 33% in breastfeeding women. It is more frequent in the first three months postpartum, especially between the second and third weeks, and is generally unilateral.

There are two factors in its etiopathogenesis: retention of breast milk, whether or not followed by bacterial infection. The most frequent germ involved is Staphylococcus aureus (generally methicillin-sensitive).

Most common risk factors

  • Spaced and/or scheduled shots
  • Mixed breastfeeding
  • Poor grip
  • Separation of mother and newborn in the first 24 hours
  • Cracks or anatomical changes in the nipple
  • Primiparity
  • Overproduction of milk
  • Previous mastitis
  • Sustained pressure on the chest (tight bra, car seat belt, or sleeping prone)
  • Prematurity

Symptoms

Symptoms may appear suddenly in one or both breasts, the most frequent are: pain, heat, swelling and a wedge-shaped blushing that outlines the affected breast lobe.

Local lesions on the nipple (irritation, cracks) may be present with intense pain, all associated with systemic symptoms such as fever, chills, and general malaise.

Diagnostic tests

Breast ultrasound is recommended in cases of poor evolution to rule out abscesses, inflammatory breast cancer or ductal cancer and breast milk culture with antibiogram if the evolution is poor after two days of correct treatment, recurrences, allergy to usual treatments, severe mastitis, recurrent mastitis, probable nosocomial origin, risk of methicillin-resistant S. aureus and mothers of premature babies.

Treatment

General measures:

  • Initiate breastfeeding from the affected breast (milk from the affected breast does not pose a risk to the infant)
  • Take frequent and effective shots
  • Massage the breast from the affected area to the nipple.
  • Cold compresses after feedings to reduce edema and pain
  • Pain control with analgesics and NSAIDs, especially Ibuprofen 400 to 600 mg every 6–8 hours, as it relieves pain and inflammation and facilitates breast drainage.

Empirical antibiotic treatment: As a general rule, it is recommended to start antibiotic therapy if symptoms persist for more than 24-48 hours after having applied the general measures described and adequate breast emptying.

Antibiotic treatment recommended for 10-14 daysCloxacillin 500-1000 mg c/4 to 6 h, amoxicillin-clavulanic acid 875/125 mg c/8h cefalexin 500 mg c/6h or cefadroxil 1 g c/12-24 h, as effective as cloxacillin and more convenient to administer (Remember, antibiotics should be taken only when prescribed and indicated by your doctor).

In case of allergy to beta-lactams, the indicated antibiotics are clindamycin, vancomycin, linezolid or cotrimoxazole.

Specific antibiotic treatment: Guided by antibiogram.

Tags: AntibioticsInfection
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