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Health » Stomach pain: When to use Buscapina and when to use Motilium?

Stomach pain: When to use Buscapina and when to use Motilium?

Not all digestive ailments are the same. Buscapina works against colic, and Motilium against nausea and indigestion.

by Wendy Lazcano
September 19, 2025
Reading time: 2 mins read
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Wendy Lazcano
Editor at Vitals Today
She is an experienced journalist who has worked in print media such as Diario de Cuba and Review Energy, as well as hosting radio (Wradio/Grupo PRISA) and television (Canal 33) programs. A specialist in politics and regulations, Wendy stands out for her ability to analyze and explain complex issues.
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When your stomach hurts, decide on the dominant symptom. If cramping is the main symptom, help. Buscopina (butylscopolamine). If nausea or vomiting predominate, the label-supported option is Motilium (domperidone). In the EU, domperidone is not indicated for “heavy digestion/indigestion.” If you experience fever, persistent pain, bleeding, or dehydration, go to the emergency room.

What type of pain is Buscapina used for: cramps and spasms?

It is used for spasms of the smooth muscle of the digestive tract and biliary tract; does not stop nausea. It is an antispasmodic/antimuscarinic that relaxes the intestine and may reduce motility. Adult dosage: 10–20 mg per dose, 3–5 times/day (max. 100 mg/day). Use as little as possible; do not prolong without diagnosis.

Typical effects: dry mouth, tachycardia, and urinary retention. Avoid if you have narrow-angle glaucoma, myasthenia gravis, megacolon/ileus, or urinary obstruction, tachycardia, or retention (e.g., due to prostatic hyperplasia). Consult if pain becomes less crampy, fever develops, or if it does not improve within 48 hours.

What ailments is Motilium used for: nausea and indigestion?

It is indicated to relieve nausea and vomiting in adults and adolescents ?12 years and ?35 kg; not for "heavy digestion" without nausea. It acts as a dopaminergic antagonist antiemetic with peripheral prokinetics. Dosage: 10 mg before meals, up to 3 times/day (max. 30 mg/day), for ?7 days without supervision.

Do not use with moderate-to-severe liver disease, prolonged QT/heart disease, electrolyte disturbances, or bradycardia. Avoid combining with drugs that prolong QT or potent CYP3A4 inhibitors (e.g., clarithromycin/erythromycin, ketoconazole/itraconazole). Special caution if over 60 years of age. Consult if vomiting persists, dehydration occurs, or blood is present.

Can I take them together?

Combining them without medical advice is not recommended: Buscapina tends to reduce motility, while domperidone tends to increase it. Prioritize the main symptom: colic/spasm ? Buscapina; nausea/vomiting ? domperidone within limits (?7 days, ?30 mg/day). For indigestion without nausea, opt for general measures (hydration, light meals) and seek medical attention if pain persists. If pain awakens at night, pregnancy, a patient aged ?65 years, fever, or does not improve within 24–48 hours, avoid self-medication and seek medical attention.

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