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Mental Health ยป Trazodone: what it is, what it's prescribed for, and how to get it

Trazodone: what it is, what it's prescribed for, and how to get it

Trazodone in Spain: what it is, what it is prescribed for and how it is dispensed with a prescription, with brands such as Deprax, and what to expect at the beginning if there is insomnia.

by Raquel Hernandez
February 8, 2026
Reading Time: 4 mins read
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Raquel Hernandez
Raquel Hernandez
Retired psychologist and writer at Vitals Today
Our mental health and scientific outreach expert. With a deep commitment to emotional well-being, Raquel writes about recent research, relevant discoveries and essential topics related to mental health.
Raquel Hernandez
Latest posts by Raquel Hernandez (see all)
  • Trazodone: what it is, what it's prescribed for, and how to get it - February 8, 2026
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Trazodone is a prescription antidepressant dispensed by pharmacies with a valid prescription, mainly indicated for major depressive episodes and mixed depression with anxiety, and it is sometimes used when insomnia is also present.

What is trazodone prescribed for?

Its main indication is the treatment of major depressive episodes and mixed states of depression and anxiety, with or without secondary insomnia. That is why it is sometimes mentioned in conversations about depression and sleep, although the decision should always be individualized in a consultation.

It's also worth noting that there are various presentations and manufacturers, but the clinical criteria don't change based on the label. What matters is the active ingredient and monitoring, especially at the beginning, when drowsiness is more likely to occur.

Do you need a prescription to buy trazodone in Spain?

Yes, trazodone is a prescription medication and pharmacies must dispense it with a prescription. If someone offers to sell it without health oversight, the risk is not only legal but also related to safety, because there are no guarantees regarding the product, its storage, or traceability.

How long does it take to see the effect?

There's no single answer because it depends on why it's prescribed and on each individual. Typically, the doctor will assess progress during checkups and adjust the plan if there's no benefit or if bothersome side effects appear.

If you experience significant drowsiness in the first few days, this is a side effect described in the package insert and is usually more noticeable at the beginning. If you have any practical questions, such as how to combine it with work or driving, it's best to discuss them with your doctor or pharmacist.

Alternatives that are usually considered in consultation

Depending on the cause, the professional may consider non-pharmacological measures if the main problem is insomnia, or, if the focus is on depression or anxiety, another antidepressant or a combination plan. The important thing is not to change treatment on your own and to review options with follow-up.

This text is for informational purposes only and does not replace medical advice. For specific instructions, dosage, duration, contraindications, and interactions, please consult the official package insert and follow the prescription and instructions of your doctor or pharmacist, as applicable.

Tags: DepressionSpain
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