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A study pioneer has confirmed the impact of HER2DX®, a genomic test for the breast cancer HER2 positive, in therapeutic decision makingPublished in the journal ESMO Real World Data and Digital Oncology, this research is the first to evaluate how HER2DX® results influence treatments for patients with early-stage HER2-positive breast cancer. The study was conducted in several hospitals in Spain and brought together 297 patients.
A breakthrough in the treatment of HER2-positive breast canceror
The results show that the test influenced treatment in almost 50% cases. In most of them, oncologists adjusted treatments based on the results obtained. This allowed therapeutic approaches to be personalized for each patient.
In fact, 75.5% of patients experienced a reduction in the intensity of chemotherapy or anti-HER2 therapy. Despite these adjustments, clinical outcomes were not compromised. These findings demonstrate the ability of HER2DX® to reduce treatment aggressiveness without affecting its efficacy. In short, HER2DX® helps personalize treatments, which improves patient care and outcomes.
Benefits of HER2DX® in clinical decision making
One of the key findings of the study is how HER2DX® facilitates the identification of patients most likely to achieve a pathological complete response (pCR). This helps oncologists choose the most appropriate therapies for each patient. In addition, oncologists reported a significant increase in their confidence in making decisions based on HER2DX® results. This increased confidence contributed to improved treatment quality.
The impact of HER2DX® on clinical practice also extends to the optimization of treatments. By reducing the need for more intensive treatments, a more personalized therapeutic approach is achieved. Therefore, the results not only benefit patients, but also provide cost savings to the health system.
