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Pain Relief ยป Meloxicam vs ibuprofen? Key differences

Meloxicam vs ibuprofen? Key differences

Practical differences between meloxicam and ibuprofen, what each is usually indicated for, what changes in prescription and packaging, and what precautions anti-inflammatories share.

by Wendy Lazcano
February 19, 2026
Reading Time: 4 mins read
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Wendy Lazcano
Editor at Vitals Today
Wendy is an experienced journalist with a background in print (Diario de Cuba, Review Energy), radio (W Radio / PRISA Group) and television (Canal 33). She specialises in politics and regulation and is known for making complex issues easy to understand.
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There is no universal โ€œbestโ€ between meloxicam and ibuprofen, because they are used in different situations and come in different pharmacy presentations, so the choice often depends on the type of pain, how long it is expected to be used, and what a professional has advised.

Meloxicam vs ibuprofen

Meloxicam and ibuprofen belong to the non-steroidal anti-inflammatory drugs, but they are not handled the same way in daily practice, mainly because of the type of problem for which they are usually indicated and how they are dispensed according to brand and presentation, with or without a prescription.

The table summarizes a general comparison, intended to provide context and not to help you decide what to take.

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If you're looking forโ€ฆIt usually fits better
Occasional pain / feverIbuprofen (depending on presentation)
Inflammatory joint painMeloxicam (usually prescribed)

What is meloxicam usually used for?

Meloxicam is mainly used for inflammatory joint problems, and its package leaflet lists indications such as acute crises of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, with an approach that is usually prescribed and reviewed by a professional depending on the case.

It is also noted that meloxicam is not the right choice when seeking immediate relief from acute pain, which helps to understand why it does not always "replace" other painkillers used occasionally.

When does it make sense to talk about ibuprofen?

Ibuprofen is widely used to relieve mild to moderate pain and fever, and brands of ibuprofen such as Espididol are presented for occasional discomfort for a few days, following the package conditions and the warnings in the leaflet.

In Spain, there are over-the-counter and prescription-only versions, so it's advisable to pay attention to the brand, dosage, and type of packaging, and ask at the pharmacy if your case falls under self-care or requires medical evaluation.

Shared risks between Meloxicam and ibuprofen

While it is sometimes considered to take meloxicam with paracetamol on the same day (depending on a professional's prescribed plan), it is generally not recommended to combine meloxicam with ibuprofen, because that would mean using two NSAIDs at the same time unless there is an explicit indication.

As a group, NSAIDs are associated with digestive effects and risks that increase when treatments are prolonged or high doses are used, and for this reason, combining two anti-inflammatories at the same time is usually avoided unless expressly indicated.

This text is for informational purposes only and does not replace medical advice. Always consult the official package insert and follow the prescription and instructions of your doctor or pharmacist regarding dosage, intervals, duration, interactions, and contraindications.

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